Symbol
Name
ID

Spred1
sprouty protein with EVH-1 domain 1, related sequence
MGI:2150016

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Vestibular schwannoma

Neurofibroma

Optic nerve glioma

Chiari type I malformation

Neoplasm of the central nervous system

Delayed speech and language development

Atypical behavior

Hyperactivity

Attention deficit hyperactivity disorder

Cognitive impairment

Short attention span

Dystonia

Brain imaging abnormality

Motor delay

Specific learning disability

Seizure

Disease(s) Associated with SPRED1

Legius syndrome

Mouse Phenotypes		nervous system phenotype	abnormal brain morphology	hydrocephaly	abnormal excitatory postsynaptic potential	reduced long-term potentiation	absent long-term depression	enhanced paired-pulse facilitation
Availability	Mouse Genotype	nervous system phenotype	abnormal brain morphology	hydrocephaly	abnormal excitatory postsynaptic potential	reduced long-term potentiation	absent long-term depression	enhanced paired-pulse facilitation
	Spred1^{em1(IMPC)Ccpcz}/Spred1^{em1(IMPC)Ccpcz}
	Spred1^tm1Hiin/Spred1^tm1Hiin	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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